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Highlighted boxes identify the study type and evidence level attained, while analysis of the key message and impacts of the trial firmly place the evidence into a practical setting for the reader. Key study features and results are examined, while the difficulties or problems associated with the trials are outlined. Loved and trusted by generations of doctors, the Oxford Handbook of Clinical Medicine and the Oxford Handbook of Key Clinical Evidence continue to be indispensable companions for the practice of modern medicine.

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